Gender Differences and White Blood Cells on Anxiety Symptoms in Type 2 Diabetes Mellitus: A Community-Based Study

Gender Differences and White Blood Cells on Anxiety Symptoms in Type 2 Diabetes Mellitus: A Community-Based Study

Wiwin Priyantari Heriningsih, Ratna Agustin, Fatin Lailatul Badriyah, Djoko Priyono, Nia Desriva, Yafi Sabila Rosyad, Yohanes Andy Rias

Gender differences and type 2 diabetes mellitus (T2DM)-associated inflammatory biomarkers are correlated with high levels of anxiety. However, no study has investigated gender differences and high level of white blood cells (WBC) on anxiety among participants with T2DM in Indonesia. We examined the roles of gender and WBCs on anxiety symptoms in T2DM. Cross-sectional study was performed on 294 patients with T2DM recruited from five community clinics with multistage cluster sampling. Depression, anxiety and Stress-21 (DASS-21) a standardized questionnaire was used to measure anxiety and WBCs was determined using an XP-100 automated hematology analyzer. The adjusted coefficients beta (coef. β) and 95% confidence interval (CI) were performed using multiple linear regression model. Statistical analyses were calculated using SPSS version 25.0, with a p value of <0.05 set as statistically significant. Famales exhibited significantly higher levels of anxiety (β=0.26, 95% CI=0.07–0.94) than male respondents. Notably, respondents with WBCs of ³7.576 had significantly higher anxiety (β=2.04, 95% CI=1.12–3.71) than patients with WBCs of <7.576. There was high prevalence of axienty symptoms in this Indonesian sample of respondents. Female and high level of WBCs exist on increasing susceptibility to anxiety symptoms among individuals with T2DM.

2021

Jurnal Aisyah: Jurnal Ilmu Kesehatan, Vol. 6, No. 2 (2021)
P-ISSN: 2502-4825 | E-ISSN: 2502-9495
DOI : 10.30604/jika.v6i2.478
https://aisyah.journalpress.id/index.php/jika/article/view/6239